Home › Abdominal Hernia › NCT03310905

Abdominal Wall Transplant

Abdominal Wall Transplantation for the Reconstruction of Abdominal Wall Defects as Adjunct to Abdominal Solid Organ Transplantation

Who can join

Ages 18 to 65 · All sexes

Inclusion Criteria:

* Candidates between 18-65 years old
* Willingness and legal ability to give consent
* Abdominal Wall in combination with another organ transplant: they must be eligible for the non-vascularized composite allograft organ transplant at Duke

Exclusion Criteria:

* Malignancy at evaluation or history of malignancy that precludes transplantation
* Pregnancy: Women who are of childbearing potential must have a negative serum pregnancy test within 48 hours of transplant and agree to use reliable contraception with two contraceptive methods for a minimum of 2 years following abdominal wall transplantation. Subjects seeking to become pregnant following 2 years will be made aware during the consent process that the effect of pregnancy on the transplanted abdominal wall and vice versa is unknown.
* Medical exclusion criteria for general anesthesia
* Ongoing substance abuse or history of untreated substance abuse

About the study

The purpose of this protocol is to determine the safety and efficacy of abdominal wall transplantation as a treatment for the reconstruction of abdominal wall defects. Abdominal wall transplantation may be performed alone or in combination with another transplant.

What is being tested

• Abdominal Wall Transplant with another solid organ transplant (procedure)
• Abdominal Wall Transplant alone (procedure)

Sponsor: Duke University · Participants: 5 · Started: May 1, 2018

Contact the study team

• Linda Cendales, MD · Phone: 919-681-7514
• Kadiyala Ravindra, MD · Phone: 919-613-9687

Official record on ClinicalTrials.gov — NCT03310905

Locations in the U.S.

Conditions

• Abdominal Hernia
• Hernia

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.