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Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients

Who can join

Up to age 17 · All sexes

Inclusion Criteria:

* 0 to \< 18 years old
* Undergoing surgery at Boston Children's Hospital under general anesthesia
* mechanically ventilated with an endotracheal tube
* Monitored with an indwelling radial arterial catheter as part of the anesthetic plan for the scheduled surgical procedure

Exclusion Criteria:

* Prematurity
* Low birth weight
* Congenital heart disease
* Left or right ventricular dysfunction
* Cardiac arrhythmia
* Pulmonary hypertension
* Preoperative parenchymal or interstitial lung disease
* Intracranial hypertension
* Poor transthoracic acoustic window
* Obesity
* Allergy to ultrasound transmission gel
* Need for single lung ventilation
* Systemic hypertension on antihypertensive medications

About the study

In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration.

It is important for an anesthesiologist to know if a child would respond to fluid administration so that they can provide the optimal intervention for low blood pressure and avoid unnecessary treatment.

What is being tested

• Lung Recruitment Maneuver (other)
• Fluid Administration (other)

Sponsor: Boston Children's Hospital · Participants: 48 · Started: Jun 21, 2018

Contact the study team

• Viviane Nasr, MD · Phone: 617-355-6225

Official record on ClinicalTrials.gov — NCT03431064

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.