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Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients
RecruitingObservational study
Incidence of Neurocognitive Deficits in Patients After Treatment for Retinoblastoma With Multiple Anesthesia Exposures
Who can join
Ages 6 to 17 · All sexes
Full eligibility criteria
Inclusion Criteria: * Age ≥ 6 and \< 17 years old Exclusion Criteria: * Diagnosis of any secondary disease associated with developmental delay * History of second cancer diagnosis * Legal Blindness * Past surgery of any type, with the exception of enucleation for retinoblastoma * Past exposure to anesthesia for surgical intervention * More than one anesthesia encounter for surgical intervention before diagnosis at MSK * Past External Beam Radiation for treatment of retinoblastoma * Past systemic chemotherapy * Non-native speaker of English; however, children whose parents speak only Spanish will be included, because the tests for parents are available in Spanish
About the study
The purpose of this study is to see if there is a difference between the development of the brain (neurodevelopment) in children who have been treated for retinoblastoma with multiple anesthetic exposures, compared with brain development in children who have never had anesthesia.
What is being tested
- Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V) (other)
- California Verbal Learning Test, Children's Version (other)
- Beery Developmental Test of Visual Motor Integration, 6th edition (other)
- Grooved Pegboard Test (other)
- Behavior Assessment System for Children/Parent Report (other)
Sponsor: Memorial Sloan Kettering Cancer Center · Participants: 75 · Started: May 7, 2018
Contact the study team
- Vittoria Arslan Carlon, MD · Phone: 212-639-2680
- David Abramson, MD · Phone: 212-639-7232
Official record on ClinicalTrials.gov — NCT03546387
Locations in the U.S.
| New York | Memorial Sloan Kettering Cancer Center, New York |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.