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Hemodynamics Monitoring During Lower Body Negative Pressure (LBNP) Induced Controlled Hypovolemia

Who can join

Ages 20 to 45 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

\* Healthy volunteers aged 20-45 with

Exclusion Criteria:

* Pregnant women
* Under 20 years of age
* Subjects with coronary artery disease, diabetes, epilepsy and hypertension

About the study

To monitor the changes in central and peripheral monitors/waveforms during gradual hypovolemia induced by lower body negative pressure in healthy volunteers.

What is being tested

• Lower body negative pressure (diagnostic test)

Sponsor: Yale University · Participants: 120 · Started: Nov 15, 2017

Contact the study team

• Aymen Alian, MD · Phone: 203-785-2802

Official record on ClinicalTrials.gov — NCT03592290

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.