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Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support

Who can join

0 Days – 17 Years · All sexes

Inclusion Criteria:

* supported on ECMO
* receiving one or a combination of the following drugs dexmedetomidine, fentanyl, midazolam or morphine as part of sedation management

Exclusion Criteria:

-none

About the study

This study will measure plasma concentrations of dexmedetomidine, fentanyl, morphine and midazolam in pediatric patients supported with extracorporeal membrane oxygenation (ECMO) aiming to understand the pharmacokinetics of these drugs in this setting.

What is being tested

• Dexmedetomidine (drug)
• Fentanyl (drug)
• Midazolam (drug)
• Morphine (drug)

Sponsor: Boston Children's Hospital · Participants: 20 · Started: Feb 8, 2019

Contact the study team

• Viviane Nasr, MD · Phone: 617-355-6225

Official record on ClinicalTrials.gov — NCT03593408

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.