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Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy

Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy/Adenoidectomy: Randomized Control Trial

Who can join

Ages 3 to 18 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* participants age 3-18 years
* ASA class 1 or 2
* elective Tonsillectomy/Adenoidectomy
* outpatient setting.

Exclusion Criteria:

* BMI \>40kg/m2
* history of renal insufficiency, chronic pain
* allergy to gabapentin
* history of developmental delay

About the study

The purpose of this pilot study: 1) to examine the use of gabapentin in reducing pain in the first 48 hours postoperatively including the total amount of narcotics mg/kg given 2) to record the time to first analgesic postoperatively and 3) to compare Wong Baker and the 0-10 numeric pain distress scale scores at 12, 24 and 48 hours postoperatively. We hypothesize one 15mg/kg (up to 600mg) dose of gabapentin will decrease mean narcotic amounts in mg/kg compared to participants who do not receive preoperative gabapentin and will demonstrate a decreased mean time to first analgesic as well as to lower mean pain scores for each age group at 12, 24 and 48 hours.

What is being tested

• Gabapentin (drug)

Sponsor: Children's Healthcare of Atlanta · Participants: 50 · Started: Jul 31, 2018

Contact the study team

• Beena Desai · Phone: 404-785-2269
• Margaret A Gettis, DNP,CPNP-PC · Phone: 404-785-8622

Official record on ClinicalTrials.gov — NCT03625011

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.