A Phase 2 Study of Home Care Following Autologous Hematopoietic Stem Cell Transplantation

Patient Inclusion Criteria:

* Scheduled to undergo an autologous hematopoietic stem cell transplant for any cancer or non-cancer illness
* Age 18-80 years
* Karnofsky Performance Scale KPS\> 80
* Able to read/write English
* A home that is deemed, upon inspection, in suitable condition to serve as a medical home, within a 90-minute driving distance of Duke

Patient Exclusion Criteria:

* Lack of a caregiver
* Pregnant women
* Patients with a documented active infection prior to starting their preparative regimen. This includes grade 3 or higher viral, bacterial, or fungal infection.
* Use of homeopathic medications, prebiotics, or probiotics that may impact gut microbiota

Caregiver Inclusion Criteria:

* Identified by patient as their primary caregiver
* Meet standard clinical criteria for being a caregiver (able to drive and take care of patient)
* Age 18-80 years

Caregiver Exclusion Criteria:

None