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Cereset Research Exploratory Study
Recruiting
Who can join
Ages 11 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Subjects must have the ability to comply with basic instructions and be able to sit still comfortably with the sensor leads attached * Subjects experiencing symptoms of stress, anxiety, or insomnia, who meet threshold scores on one or more self-reported inventories for the same. This includes the Insomnia Severity Index (ISI, ≥ 8), the Perceived Stress Index (PSS, ≥ 14), or the Generalized Anxiety Disorder 7-item (GAD-7, ≥ 5) scale. Exclusion Criteria: * Unable, unwilling, or incompetent to provide informed consent/assent. * Physically unable to come to the study visits, or to sit comfortably in a chair for up to 1.5 hours. * Severe hearing impairment (because the subject will be using ear buds during CR). * Weight is over the chair limit (285 pounds). * Currently in another active intervention research study. * Prior use of HIRREM, Brainwave Optimization, Cereset, or a wearable configuration of the same (B2, or B2v2) within the last 3 years. * Prior use of electroconvulsive therapy (ECT). * Prior use of transcranial magnetic stimulation (TMS), transcranial direct current stimulation (TDCS), alpha stimulation, neurofeedback, biofeedback, or deep brain stimulation (DBS) within one month before enrollment. * Known seizure disorder.
About the study
The purpose of this study is to evaluate the use of Cereset Research to improve autonomic function in participants with symptoms of stress, anxiety, or insomnia.
What is being tested
- Active CR (device)
Sponsor: Wake Forest University Health Sciences · Participants: 200 · Started: Apr 12, 2019
Contact the study team
- Kenzie Brown · Phone: 336-716-9447
Official record on ClinicalTrials.gov — NCT03777267
Locations in the U.S.
| North Carolina | Wake Forest University Health Scienc\ess, Winston-Salem |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.