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Detection of Unsuspected Small Airways Obstruction in Cystic Fibrosis
The Measurement and Analysis of Maximal Expiratory Flow Volume Loops at Low Lung Volumes in Children With Cystic Fibrosis and Normal Routine Lung Function.
Who can join
Ages 5 to 40 · All sexes
Full eligibility criteria
Inclusion Criteria: Heterozygote or homozygote patients with cystic fibrosis with normal routine pre bronchodilator spirometry including normal FEV1(L), FVC(L) and FEV1/FVC%. Exclusion Criteria:Heterozygote or homozygote patients with cystic fibrosis with ABNORMAL routine pre bronchodilator spirometry \-
About the study
Goal is to physiologically detect unsuspected small airways obstruction in children and adults with treated heterozygous and homozygous cystic fibrosis. Unsuspected refers to normal routine pre bronchodilator spirometry including normal FEV1(L), FVC (L). and FEV1/FVC%. This is a retrospective study.
What is being tested
- spirometry (diagnostic test)
Sponsor: Gelb, Arthur F., M.D. · Participants: 100 · Started: Apr 25, 2018
Contact the study team
- Arthur F Gelb, MD · Phone: 562-565-5333
- Vicki Masson, MD · Phone: 631-741-0549
Official record on ClinicalTrials.gov — NCT03839992
Locations in the U.S.
| California | Arthur F Gelb MD, Lakewood Miller Children's Hospital and Long Beach Medical Center, Long Beach |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.