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Study of Endocrine-Related Conditions and Physiology

The Evaluation and Management of Endocrine-Related Conditions and Physiology

Who can join

Ages 18 to 90 · All sexes

* INCLUSION CRITERIA:

In order to be eligible to participate in this study, an individual must meet all the following criteria:

* Adult men and women age 18 years or older.
* Known or suspected endocrine disorders requiring clinical screening, management and/or treatment and follow-up.
* Stated willingness to comply with all study procedures and availability for the duration of the study

EXCLUSION CRITERIA:

* Unstable participants and participants with severe organ failure, or those with a condition or medical treatment that may affect/limit the endocrine work-up and exhaust Clinical Center, IETP resources will be excluded if appropriate.
* Inability of a subject to adhere to a proposed schedule of visits.
* Inability to provide informed consent.

About the study

Background:

Endocrine disorders involve changes to glands that produce hormones. Hormones are released by these glands into the blood so they can direct the function of other tissues in the body. Researchers want to study people who may have endocrine disorders. They want to learn more about the conditions that affect endocrine glands.

Objective:

To study adults with a variety of endocrine disorders for research and physician education.

Eligibility:

Adults ages 18 and older who have an endocrine or metabolic-related disorder

Healthy volunteers 18 and older

Design:

Participants will be screened with a review of their medical records.

Participants will have a physical exam and medical history.

The length of the study and the schedule will vary by participant. Tests may include:

Blood and urine tests

Stool and saliva samples

Imaging studies: Participants will lie on a table while a machine takes pictures of the body. They may be injected with a substance to make their organs more visible in the pictures.

Tests of endocrine tissue function

Consultation with other specialists

Sleep study

Medical photographs

Participants may be treated for their endocrine disorder. This could include:

Surgery. If tissue is removed during surgery, it may be studied.

Radiation

Medicine

Participants may have genetic testing. This will be done with a small amount of blood, cells from a cheek swab, or saliva.

Sponsoring Institution: National Institute of Digestive, Diabetes and Kidney Disease

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What is being tested

• Creation of side holes in catheters for adrenal vein sampling (device)

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Participants: 1,000 · Started: Mar 27, 2019

Contact the study team

• Raven N McGlotten, R.N. · Phone: (301) 827-0190
• Lynnette K Nieman, M.D. · Phone: (301) 496-8935

Official record on ClinicalTrials.gov — NCT03867448

Locations in the U.S.

Conditions

• Endocrine Diseases

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.