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Oxybutynin for Post-surgical Bladder Pain and Urgency

RecruitingPhase 3

Who can join

Ages 4 to 8 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Patients who will undergo bladder surgery that requires an indwelling bladder catheter after surgery.
* Age Range: Four to 8 years of age are eligible for the study.

Exclusion Criteria:

* Patients who have had prior bladder surgery.
* Patients who have neurologic disease that could impair bladder sensation.
* Patients who are already taking antimuscarinic or antispasmodic medications.
* Patients with glaucoma, any neurologic disease, dementia, impaired mentation or disorder of the central nervous system.
* Patients taking any medication that affects the central nervous system such as antidepressant, anxiolytic or antipsychotic medications.
* Less than four years of age cannot have the transdermal patch due to fixed dose. Over 8 years of age: less than 5% of our patients, who undergo this surgery, are over 8 years of age and is usually a rare adolescent. Data in an older cohort may confuse the results since they respond differently to bladder surgery due to larger incision and longer hospital stay with a catheter.

About the study

Bladder pain and urgency are common after bladder surgery. The objective is to determine if transdermal administration is superior to oral administration in alleviating pain and urgency.

What is being tested

Sponsor: University of California, Davis · Participants: 100 · Started: Sep 1, 2021

Contact the study team

Official record on ClinicalTrials.gov — NCT03952299

Locations in the U.S.

CaliforniaUniversity of California Davis Medical Center (UCDMC), Sacramento

Conditions

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.