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Vicryl Rapide Versus Nonabsorbable Suture
Vicryl Rapide Versus Nonabsorbable Suture in Repair of Simple Traumatic Extremity and Trunk Lacerations in Adult Patients
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria:
* Patient 18-years or older
* single laceration on trunk or extremity requiring suture closure
* laceration length \> 2-cm
* wound to be closed with simple interrupted sutures
Exclusion Criteria:
* High infection potential
* Must have one of the following:
* puncture wound
* -highly contaminated
* devitalized tissue requiring sharp debridement
* -bite wounds
* -\> 24-hours-old
* Low likelihood of good cosmesis
* Must have one of the following:
-dehisced wound from previous wound closure
* -wound
* -crush wound
* -soft tissue deficit limiting complete apposition of wound edges
* -significant overlying macerated/abraded tissue
* Underlying tendon or cartilage involvement
-Wound greater than 10 cm in length
* Significant wound healing problems
* Must have one of the following:
* keloid formers
* chronic steroid use
* other: \_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_ -Inability to give written consent
* Must have one of the following:
* non-English or non-Spanish speaker
* altered mental status
* incarcerated patient
* No telephone number or unlikely to return for 3-month follow-up
* Must have one of the following:
* homeless
* psychiatric patient,
* nursing home patient,
* other: \_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
* More than one laceration needing suture repair on trunk or extremity (i.e. appropriate to proceed if second laceration is to face/neck)About the study
This will be a prospective, randomized controlled trial assessing noninferiority of Vicryl Rapide compared to nonabsorbable suture. The study will be conducted in the Community Regional Medical Center emergency department (ED). The aim of this study, then, is to prospectively determine if 3-month cosmesis for traumatic laceration repair of trunk/extremity lacerations in adult patients with Vicryl Rapide is noninferior to nonabsorbable suture.
What is being tested
- Vicryl Rapide absorbable suture (device)
Sponsor: University of California, San Francisco · Participants: 96 · Started: Sep 26, 2019
Contact the study team
- Brian Chinnock, MD · Phone: 559-499-6440
- Jannet Castaneda, BA · Phone: 559-994-5893
Official record on ClinicalTrials.gov — NCT04056013
Locations in the U.S.
| California | Community Regional Medical Center, Fresno Community Regional Trauma and Burn Center, Fresno |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.