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Outcomes for Lumbar Decompressions With Use of Liposomal Bupivicaine

A Double Blinded Randomized Control Trial in Outcomes for Lumbar Decompressions With Use of Liposomal Bupivicaine

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

1. Male or Female
2. Adult (≥18 yo)
3. Lumbar stenosis

Exclusion Criteria:

1. Co-morbidities precluding surgery
2. ≤18 yo
3. Pregnant
4. Breastfeeding
5. Need for instrumented fusion
6. Prisoners
7. Intra-operative CSF leak (identified by gush of CSF)
8. Daily pre-operative opioid use of \> 25 morphine Eq/day
9. Previous lumbar surgery at indicated level

About the study

Evaluate the benefit of using liposomal bupivicaine in lumbar laminectomies in terms of length of stay, IV narcotic use, 30-day narcotic use, visual analog score (VAS) and 30-day readmissions

What is being tested

• Liposomal bupivacaine (drug)

Sponsor: University of Colorado, Denver · Participants: 100 · Started: Sep 8, 2019

Contact the study team

• Jens-Peter Witt, MD, PhD · Phone: 303-724-2306
• Akal Sethi, MD · Phone: 303-724-1995

Official record on ClinicalTrials.gov — NCT04066296

Locations in the U.S.

Conditions

• Spinal Stenosis

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.