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Mechanisms Underlying the Protective Vascular Effects of Dietary Potassium in Humans

Who can join

Ages 18 to 45 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* healthy
* normal blood pressure
* normal resting ECG

Exclusion Criteria:

* hypertension
* history of heart disease
* diabetes
* kidney disease
* obese (BMI ≥30)
* significant weight changes in the last 6 months
* use of tobacco products
* pregnant
* on a special diet (gluten free; vegan)
* take any medications for the above conditions
* endurance trained athletes

About the study

Americans continue to consume high amounts of sodium. Potassium is notable for its blood pressure lowering effects but less is known regarding its effect on the vasculature. This investigation seeks to determine the role of dietary potassium on the vasculature in the presence of a high sodium diet in salt-resistant adults.

What is being tested

• Moderate Potassium/Low Sodium Diet (other)
• Moderate Potassium/High Sodium Diet (other)
• High Potassium/High Sodium Diet (other)

Sponsor: University of Delaware · Participants: 90 · Started: Jan 16, 2020

Contact the study team

• Shannon L Lennon, PhD · Phone: (302)831-2798
• Shannon L Lennon, PhD · Phone: 3028312798

Official record on ClinicalTrials.gov — NCT04101188

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.