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Biospecimen Analysis in Detecting Chemical Concentrations in Patients With Chronic or Infectious Diseases Receiving Meditations
Pilot Study to Evaluate Substances in Sweat, Saliva, and Blood
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Scheduled to receive medications including, but not limited to, cyclophosphamide, mycophenolic acid, mycophenolate mofetil, metformin or busulfan (any dose, any number of doses, any dosing frequency) as part of treatment at any time. Patients with chronic or infectious diseases can participate * Willingness to: * Provide blood, sweat, and saliva samples * Permit medical record review Exclusion Criteria: * Pilocarpine allergy * Difficulty with understanding written English
About the study
This trial collects and analyzes sweat and saliva samples compared to blood in detecting chemical concentrations in the body in patients with chronic or infectious diseases receiving medications. Wearable sweat sensors are capable of monitoring electrolytes and metabolites (sodium, potassium, glucose, lactate, etc.) for health monitoring and disease diagnosis. Designing wearable sweat sensors capable of providing information regarding drug administration may be challenging due to ultralow concentrations in biofluids. This trial seeks to determine if the use of a smart wristband can accurately measure the levels of chemicals and substances in sweat.
What is being tested
- Biospecimen Collection (procedure)
- Medical Chart Review (other)
- Questionnaire Administration (other)
Sponsor: City of Hope Medical Center · Participants: 100 · Started: Nov 9, 2018
Contact the study team
Official record on ClinicalTrials.gov — NCT04160429
Locations in the U.S.
| California | City of Hope Medical Center, Duarte |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.