Treatment Results for Patients With Central Centrifugal Cicatricial Alopecia (CCCA): a Multicenter Prospective Study
RecruitingPhase 4
Who can join
Ages 18 to 60 · Women
Full eligibility criteria
Inclusion Criteria: * African-American women, ages 18-60 years old * with a clinical diagnosis and biopsy-proven CCCA, with Central Scalp Alopecia Scale severity 1 through 4 will be included in this study * These subjects will be seen and treated in Wake Forest Baptist Health Dermatology Outpatient Clinic Exclusion Criteria: * Patients with other forms of hair loss in addition to CCCA will be excluded * Other patients to be excluded are those with other forms of inflammatory scalp disease (with the exception of mild seborrheic dermatitis) * patients who have had topical treatment for CCCA within the past 4 months (including topical steroids, topical minoxidil, or any other topical hair regrowth medication) * patients who have been on a long-term oral antibiotics for hair loss within the past year * patients who have undergone more than two rounds of intralesional steroid injections to the scalp in the past one year.
About the study
The objective of this study is to examine photos of CCCA patients taken before and after treatment to compare treatment outcomes between different treatment groups
What is being tested
- Topical steroid class I-II (drug)
- Triamcinolone Acetonide (drug)
- Doxycyline (drug)
- Minoxidil (drug)
Sponsor: Wake Forest University Health Sciences · Participants: 250 · Started: Apr 30, 2018
Contact the study team
- Amy J McMichael, MD · Phone: 336.716.3926
- Judy Holbrook, CRC · Phone: 336.716.8991
Official record on ClinicalTrials.gov — NCT04207931
Locations in the U.S.
| North Carolina | Wake Forest Baptist Health Department of Dermatology, Winston-Salem |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.