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OCT in Fuchs' Dystrophy
RecruitingObservational study
Evaluating Corneal Edema in Fuchs' Endothelial Dystrophy Using Optical Coherence Tomography
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Damaged or diseased corneal endothelium from Fuchs' or PBK * Willingness to commit to required study visits Exclusion Criteria: * Prior Endothelial Keratoplasty (EK) or any other surgery except uncomplicated cataract surgery * Presence of a condition that increases the probability for treatment failure (e.g., heavily vascularized cornea, uncontrolled uveitis) * Other primary endothelial dysfunction conditions (e.g., posterior polymorphous corneal dystrophy and congenital hereditary corneal dystrophy, iridocorneal endothelial syndrome) * Central sub-epithelial or stromal scarring that could impact post-operative clarity assessment * Peripheral anterior synechiae in the angle greater than 3 clock hours * Hypotony * Uncontrolled glaucoma * Visually significant optic nerve or macular pathology
About the study
This is an observational study using optical coherence tomography (OCT) technology to quantify corneal edema in Fuchs' endothelial dystrophy and predict refractive shift from resolving corneal edema after surgical treatments.
Sponsor: Oregon Health and Science University · Participants: 60 · Started: Jun 26, 2020
Contact the study team
- Humberto Martinez, COT · Phone: 503-494-7712
- Denzil Romfh, OD · Phone: 503-494-4351
Official record on ClinicalTrials.gov — NCT04258787
Locations in the U.S.
| Oregon | Oregon Health & Science University, Portland |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.