Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke
Recruiting
Who can join
Ages 21 to 100 · All sexes
Full eligibility criteria
Inclusion Criteria: * Age at enrollment is 21 or older * Hemiparesis from first ever stroke affecting arm movement at least 6 months prior to screening * Severe to moderate motor impairment (FMA-UE of 7-40) * At least some voluntary shoulder and elbow muscle activation Exclusion Criteria: * Inability to follow instructions of the MyoCI task * Visual impairment (such as hemianopia) preventing full view of screen * Anesthesia or neglect in the affected arm, or visual hemineglect (score of 2 on the NIH Stroke Scale Extinction and Inattention subtest) * Participation in another study on the affected arm within 6 weeks of enrollment or any pharmacological study * Inability to understand or follow commands in English due to aphasia or other reason * Diffuse or multifocal infarcts in both hemispheres * Substantial arm pain preventing participation for 90 minutes a day * Spasticity treatment (pharmacological or Botox) within last 3 months * Ferromagnetic implants that are MRI incompatible
About the study
This study will examine the combination of myoelectric computer interface (MyoCI) training with targeted memory reactivation (TMR) in chronic stroke survivors. The study aims to determine whether this training-plus-sleep combination will generalize to improve arm motor function over an extended training protocol in stroke survivors.
What is being tested
- Targeted Memory Reactivation (TMR) (other)
Sponsor: Northwestern University · Participants: 70 · Started: Feb 25, 2020
Contact the study team
- Marc W Slutzky, MD/PhD · Phone: 312-503-4653
Official record on ClinicalTrials.gov — NCT04312269
Locations in the U.S.
| Illinois | Northwestern University, Chicago |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.