Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.
Targeted Transcranial Direct Current Stimulation to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia
Who can join
Ages 25 to 85 · All sexes
Full eligibility criteria
Inclusion Criteria: 1. aged 25-85 2. must be greater than 6 months post-stroke 3. must have a diagnosis of aphasia based on impaired performance on the Western Aphasia Battery-Revised, Boston Naming Test, or during discourse production 4. must be left-hemisphere dominant as demonstrated by aphasia onset subsequent to left hemisphere damage 5. must be stimulable for naming Exclusion Criteria: 1. comorbid neurological disease. 2. damage to the anterior right hemisphere. 3. significant mood disorder. 4. substance/alcohol dependence or abuse within the past year 5. presence of any implanted electrical device or contraindications to tDCS or MRI 6. recent medical instability (within 4 weeks) 7. pregnancy
About the study
62 patients who are one year post stroke and have Aphasia as a result of that stroke will be recruited. Participants will have 4 assessment sessions and 15 treatment sessions. The TDCS will be to right Inferior Frontal Gyrus (IFG) (25 active, 25 sham) for 15 days. A combined semantic feature analysis/phonological components analysis treatment will be paired with the stimulation. Two assessment sessions will be pretreatment, 1 session immediately post-treatment, and 1 session at 3 months follow-up.
What is being tested
- Active Comparator: Experimental: Active cathodal tDCS + language training (device)
- Sham Comparator: Placebo cathodal tDCS + Speech and language (behavioral)
Sponsor: University of New Mexico · Participants: 50 · Started: Oct 18, 2022
Contact the study team
- Jessica Richardson, Ph.D. · Phone: 505 277-1765
- Honey Hubbard · Phone: 505-433-7766
Official record on ClinicalTrials.gov — NCT04432883
Locations in the U.S.
| New Mexico | University of New Mexico Center for Brain Recovery and Repair, Albuquerque |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.