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The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation
RecruitingObservational study
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Subject Age is \> 18 * Subject with a Head CT that demonstrates an acute, spontaneous, primary, supratentorial ICH of volume \> 20 mL, assessed via standard of care techniques * Subject Surgery can be initiated within 24 hours of the last known well time or, in patients with wake-up onset, within 24 hours of the time the patient awoke with symptoms. * Subject has a NIHSS score \> 5 * Subject has a baseline Modified Rankin Scale (mRS) Score ≤ 2 * Subject with a CT Angiography demonstrating no vascular malformation Exclusion Criteria: * Subject has an underlying vascular lesion defined as causative source of ICH * Subject has a profound neurological deficit defined as fixed/dilated pupils or bilateral extensor motor posturing * Subject has an Infratentorial or brainstem ICH * Subject has a known life expectancy \< 6 months * Subject has an uncorrectable coagulopathy * Subject has a mechanical heart valve * Subject is pregnant * Subject participates in another concurrent interventional clinical trial * Subject who is unable to meet study follow-up requirements
About the study
This registry will study the use of the Aurora® Surgiscope to provide surgical access and visualization in minimally invasive removal of hematoma in the brain. Many methods of hematoma removal are available and will be based on surgeon preference. The impact of patient selection and time to surgery from last known well time will be explored.
What is being tested
- Aurora Surgiscope System (device)
Sponsor: Integra LifeSciences Corporation · Participants: 500 · Started: Oct 23, 2020
Contact the study team
- Habib Nacer-Chérif · Phone: +33626190029
Official record on ClinicalTrials.gov — NCT04494295
Locations in the U.S.
| California | Providence Health, Burbank |
| Florida | University of Miami, Miami University of South Florida, Tampa |
| Illinois | Rush University Medical Center, Chicago |
| Maryland | MedStar Health Research Institute, Baltimore (Not yet recruiting) |
| Missouri | University of Missouri, Columbia Washington University in St. Louis, St Louis |
| New Jersey | JFK university, Edison |
| New York | University at Buffalo, Buffalo Icahn School of Medicine at Mount Sinai, New York |
| North Carolina | University of North Carolina, Chapel Hill |
| Ohio | Cleveland Clinic, Cleveland |
| Oklahoma | University of Oklahoma, Oklahoma City |
| Pennsylvania | Pennsylvania State University, Hershey |
| South Carolina | Prisma Health - Upstate, Greenville |
| Texas | UT Health, Houston (Not yet recruiting) |
| Utah | University of Utah, Salt Lake City |
| Washington | University of Washington - Harborview, Seattle |
From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.