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How is Social Connection Represented in the Brain?

RecruitingObservational studyHealthy volunteers welcome

Using the Brain to Reveal Mental Representations of Subjective Connection

Who can join

Ages 18 to 65 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* safe for MRI scanning
* not taking psychiatric medication

Exclusion Criteria:

* not safe for MRI scanning
* taking psychiatric medication

About the study

Nearly half of the U.S. population sometimes or always experiences loneliness, which is alarming given that loneliness confers risk for negative mental and physical health outcomes. Extensive research suggests loneliness is characterized by subjective isolation: many lonely individuals maintain a number of relationships but still report feeling lonely. The goal of this proposal is to use functional magnetic resonance imaging to reveal how the brain represents our subjective connection to and isolation from other people, which will ultimately inform optimal ways to intervene to reduce loneliness.

What is being tested

Sponsor: Columbia University · Participants: 248 · Started: Apr 1, 2021

Contact the study team

Official record on ClinicalTrials.gov — NCT04577911

Locations in the U.S.

New YorkColumbia University Irving Medical Center, New York

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.