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Registry for Intra-Operative Radiotherapy During Breast Conserving Surgery in Patients With Early Stage Breast Cancer
Research Registry for Intra-Operative Radiotherapy (IORT) During Breast Conserving Surgery in Patients With in Situ and Early Stage Breast Cancer
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Clinical stage Tis, T1, or T2(≤ 3cm), N0, M0 (AJCC Classification) * Unifocal Disease * Candidate for breast-conserving surgery * Recommended treatment by multidisciplinary team Exclusion Criteria: * Clinical stage T3-4, N1-3, M1 * Multifocal disease
About the study
This is a prospective, registry study that will enroll all women with early stage breast cancer who will be treated with intraoperative radiotherapy (IORT) during breast-conserving surgery. The purpose of this study is to further validate the long-term effectiveness and safety of this treatment method. We aim to assess short and long-term patient outcomes associated with IORT, including perioperative complications, local and distance disease recurrences, as well as disease-free survival and overall survival.
What is being tested
- Intraoperative Radiation Therapy (IORT) (radiation)
Sponsor: Saint John's Cancer Institute · Participants: 1,000 · Started: Oct 3, 2018
Contact the study team
- Janie Grumley, MD · Phone: (310) 582-7100
Official record on ClinicalTrials.gov — NCT04603209
Locations in the U.S.
| California | John Wayne Cancer Institute, Providence Saint John's Health Center, Santa Monica |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.