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Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD)

RecruitingObservational study

Who can join

All ages · All sexes

Full eligibility criteria
Inclusion Criteria:

* Genetically confirmed FSHD (types 1 or 2) or clinical diagnosis of FSHD with characteristic findings on exam and an affected parent or offspring.

Exclusion Criteria:

* Unwilling or unable to provide informed consent.
* Any other medical condition which in the opinion of the investigator would interfere with study participation.

About the study

The primary goal of this proposal is to collect motor and functional outcomes specific to FSHD over time. By collecting measures specific to FSHD, this will help ensure the best level of clinical care is being provided. Also, the hope is to speed up drug development by gaining a better understanding of how having FSHD impacts motor function and other health outcomes (i.e. breathing, wheelchair use, etc.) and how big a change in motor function would be clinically meaningful to those with FSHD.

Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD) will have approximately 450 FSHD participants followed for a minimum of 3 years. A subset of MOVE FSHD participants, approximately 200, will participate in the MOVE+ sub-study which includes whole body MRI and reachable workspace, as well as optional muscle biopsy and wearable device (US participants only).

Sponsor: University of Kansas Medical Center · Participants: 450 · Started: Dec 15, 2020

Contact the study team

Official record on ClinicalTrials.gov — NCT04635891

Locations in the U.S.

CaliforniaDavid Geffen School of Medicine at UCLA, Los Angeles
Neuromuscular Disorders Program at Stanford University School of Medicine, Stanford
ColoradoUniversity of Colorado Anschutz Medical Campus, Aurora
FloridaUniveristy of Florida Gainesville, Gainesville
IowaUniversity of Iowa, Iowa City
KansasUniveristy of Kansas Medical Center, Kansas City
MarylandKennedy Krieger Institute, Baltimore
New YorkUniversity of Rochester Medical Center, Rochester
North CarolinaDuke University - Lenox Baker Children's Hospital, Durham
OhioThe Ohio State University Medical Center, Columbus
TexasAustin Neuromuscular Center, Austin
Univeristy of Texas Southwestern Medical Center, Dallas
University of Texas Health San Antonio, San Antonio (Not yet recruiting)
UtahUniversity of Utah, Salt Lake City
VirginiaVirginia Commonwealth University, Richmond
WashingtonUniversity of Washington Medical Center, Seattle

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.