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Telerehabilitation for Aphasia (TERRA)
Center for the Study of Aphasia Recovery (C-STAR): Telerehabilitation for Aphasia (TERRA)
Who can join
Ages 21 to 80 · All sexes
Full eligibility criteria
Inclusion Criteria: 1. Participants must have sustained a left hemisphere ischemic or hemorrhagic stroke at least 12 months prior to enrollment. 2. Participants must primarily speak English for at least the past 20 years. 3. Participants must be capable of giving informed consent or indicating another to provide informed consent. 4. Participants must be between 21-80 years of age. 5. Participants must be magnetic resonance imaging (MRI) compatible (e.g., no metal implants, not claustrophobic) on a 3-Tesla (3T) scanner. Exclusion Criteria: 1. Participants must not have previous neurological disease affecting the brain (e.g. history of traumatic brain injury). 2. Participants must not have severely limited speech production (severe unintelligibility) and/or auditory comprehension that interferes with adequate participation in the therapy provided (i.e., WAB-R Spontaneous Speech rating scale score of 0-1 or WAB-R Comprehension score of 0-1). 3. Participants must not have a history of stroke to the right hemisphere of the brain. 4. Participants must not have a bilateral, cerebellar or brainstem stroke. 5. Participants must not have anything that makes them be 3T MRI incompatible 6. Insufficient intelligible speech to provide accurate responses with discourse/naming.
About the study
Speech-language therapy is generally found to be helpful in the rehabilitation of aphasia. However, not all patients with aphasia have access to adequate treatment to maximize their recovery. The goal of this project is to compare the efficacy of telerehabilitation or Aphasia Remote Therapy (ART) to the more traditional In-Clinic Therapy (I-CT).
What is being tested
- Semantically-focused therapy tasks (behavioral)
- Phonologically-focused therapy tasks (behavioral)
Sponsor: University of South Carolina · Participants: 100 · Started: May 5, 2021
Contact the study team
- Sara Sayers, M.S. · Phone: 803-777-2693
- Kelli Powell, B.S. · Phone: 803-777-5051
Official record on ClinicalTrials.gov — NCT04682223
Locations in the U.S.
| South Carolina | University of South Carolina Aphasia Lab, Columbia |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.