Home › Cleft Lip and Palate › NCT04771156

Ketorolac in Palatoplasty

Ketorolac in Palatoplasty: A Randomized Blinded Controlled Trial.

Who can join

6 Months · All sexes

Inclusion Criteria:

-Patient with Cleft palate (Complete and incomplete), with or without cleft lip, unilateral or bilateral

Exclusion Criteria:

* Syndromic Cleft Palate patients
* Previous palatoplasty
* Major unrepaired cardiac malformation
* History of GI complications (GI Bleed, Gastric Ulceration)
* History of Renal disorder
* History of coagulopathy (As contraindication to NSAID use)
* Feeding tube dependency
* Patients whose parents refuse to consent to randomization

About the study

The purpose of this study is to see if the addition of IV Ketorolac to usual care multi-modal pain therapy compared to usual care will improve oral intake post-operatively

What is being tested

• Ketorolac (drug)
• Placebo (drug)

Sponsor: The University of Texas Health Science Center, Houston · Participants: 74 · Started: Sep 17, 2021

Contact the study team

• Matthew R Greives, MD,MS,FACS · Phone: (713) 500-7275

Official record on ClinicalTrials.gov — NCT04771156

Locations in the U.S.

Conditions

• Cleft Lip and Palate

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.