Home › Glioblastoma › NCT04780009

Loupe-Based Intraoperative Fluorescence Imaging

Loupe-Based Intraoperative Fluorescence Imaging for the Guidance of Brain Tumor Surgery

Who can join

Ages 18 to 90 · All sexes

Inclusion Criteria:

* adults with brain malignant gliomas undergoing resection
* at least 18 years of age
* able to understand the consent

Exclusion Criteria:

* pregnant women
* under 18 years of age
* patients undergoing emergency surgery
* inability to give consent due to dysphagia or language barrier

About the study

Glioblastoma multiforme (GBM) and anaplastic astrocytoma (AA) are the most common primary malignant brain tumors. Survival of patients with these brain tumors is directly related to the extent of resection. Consequently, a great deal of effort has been directed at developing techniques and technologies that allow more extensive, safe resections.

This study will test a loupe-based wearable device in the clinical setting and compare its accuracy with a large operative microscope to identify tumor tissues. Postoperative histopathological analysis on tumor tissues will be used as gold standards for comparison. The outcome from this study will be a low-cost, miniaturized, easy-to-operate, loupe-based fluorescence imaging device for intraoperative guidance of brain tumor resection with the same level of accuracy as the large microscope.

Sponsor: Guoqiang Yu · Participants: 30 · Started: Nov 17, 2017

Contact the study team

Official record on ClinicalTrials.gov — NCT04780009

Locations in the U.S.

Conditions

• Glioblastoma
• Astrocytoma

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.