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Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome

Efficacy of Peppermint Oil in a Randomized, Single-Blind, Placebo Controlled Trial in Women With Interstitial Cystitis/Bladder Pain Syndrome

Who can join

Ages 18 to 65 · Women · Healthy volunteers welcome

Inclusion Criteria:

* Women ages 18-65 years old
* Diagnosed with IC/BPS for at least one month prior to study enrollment

Exclusion Criteria:

* Culture proven urinary tract infection within 1 month of randomization
* Gross hematuria
* Currently pregnant or breastfeeding
* Unable to speak and read English
* History of allergic reaction to peppermint, coconut or enteric coating
* History of malabsorption syndrome
* History of gastroparesis
* History of gastric bypass surgery
* History of gastrointestinal, genitourinary or pelvic cancer in the last 5 years
* History of insulin dependent diabetes
* History of active urinary stone disease

About the study

The purpose of this study is to assess the use of peppermint oil as a treatment for Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS).

What is being tested

• Peppermint oil (drug)
• Coconut Oil (drug)

Sponsor: University of Louisville · Participants: 100 · Started: Sep 15, 2021

Contact the study team

• Jenna Warehime, DO · Phone: 502-588-7660

Official record on ClinicalTrials.gov — NCT04845217

Locations in the U.S.

Conditions

• Interstitial Cystitis

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.