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Dietary Intervention to Mitigate Adverse Consequences of Night Work

Who can join

Ages 18 to 45 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* 18-45 yr old
* BMI 20.0-29.9
* European/Hispanic/African-American ancestry
* No acute, chronic or debilitating medical conditions (e.g. metabolic, cardiovascular, respiratory, neurological, cancers, etc.)

Exclusion Criteria:

* Currently smoking/vaping or 5 or more years of smoking/vaping
* History of drug or alcohol dependency
* History of psychiatric illness or disorder

About the study

The goal of this clinical trial is to test whether our dietary intervention can prevent or lessen the negative health effects of night shift work in healthy participants.

Participants will:

* complete 2 inpatient stays * be provided with identical meals * have frequent blood draws * provide urine, saliva, stool and rectal swab samples

What is being tested

• dietary intervention (behavioral)

Sponsor: Brigham and Women's Hospital · Participants: 24 · Started: Mar 29, 2023

Contact the study team

• Megan Munn · Phone: 6175258259
• Han-Chow Koh, PhD · Phone: 6172780924

Official record on ClinicalTrials.gov — NCT04868526

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.