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Neural Correlates of Real World Spatial Navigation in Humans
Who can join
Ages 18 to 90 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * 18 years of age or older and has undergone RNS system placement * Willing to provide informed consent and participate the study * Ability to read and write English fluently Exclusion Criteria: * Unwilling to provide informed consent
About the study
The purpose of this study is to understand the neural mechanisms that support real world spatial navigation in humans using deep brain recordings and stimulation during virtual reality (VR), augmented reality, and real world memory tasks. We will determine the cognitive (i.e., memory) and behavioral (i.e., body, head, eye position and movement) factors that modulate deep brain activity and the consequent effects of memory-enhancing deep brain stimulation.
What is being tested
- Deep Brain Stimulation (device)
- Memory and spatial navigation tasks (behavioral)
- Physiological Signals (behavioral)
- Questionnaires and Assessments (behavioral)
Sponsor: Duke University · Participants: 70 · Started: Sep 30, 2020
Contact the study team
- Aaron Halvorsen, PhD · Phone: 9196812577
- Sonja Hiller, MS · Phone: 919-681-2577
Official record on ClinicalTrials.gov — NCT04874220
Locations in the U.S.
| California | University of California, Los Angeles, Los Angeles |
| North Carolina | Duke University, Durham |
From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.