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Motor Training for Infants With Cerebral Palsy
Recruiting
Motor Training Intervention for Infants at High-Risk for Cerebral Palsy: Feasibility and Acceptability
Who can join
3 Months – 8 Months · All sexes
Full eligibility criteria
Inclusion Criteria: * Age at enrollment: between 3-8 months corrected age * Caregivers fluent in English * Preterm infants with objectively defined severe diffuse white matter abnormality on MRI at term OR * High-risk infants (e.g., preterm, neonatal hypoxic-ischemic encephalopathy, perinatal stroke) with moderate-severe injury on structural MRI or cranial ultrasound (e.g., basal ganglia/thalamic signal intensity, cystic periventricular leukomalacia, encephalomalacia, large stroke, and/or severe intraventricular/periventricular hemorrhage) at around term-equivalent age or before Neonatal Intensive Care Unit discharge AND either: * "Absent" fidgety movements based on the Prechtl General Movement Assessment (GMA) between 3-4 months corrected age OR * A score of 56 or below on the Hammersmith Infant Neuromotor Examination (HINE) between 3-6 months corrected age (31) Exclusion Criteria: * Medical conditions that restrict active participation such as oxygen dependence * Infants with significant visual deficits defined by the inability to track an object horizontally * Living in a remote location prohibiting drives to the hospital every other week.
About the study
The intervention in this study, Let's Move, is a motor intervention for infants at risk for cerebral palsy. We will test the feasibility and acceptability of the intervention as well as preliminary effectiveness.
What is being tested
- Let's Move Motor Intervention (other)
Sponsor: Children's Hospital Medical Center, Cincinnati · Participants: 35 · Started: Jan 7, 2022
Contact the study team
- Karen Harpster, PhD, OTR/L · Phone: 513-803-3604
- Nehal A Parikh, DO, MS · Phone: 513-517-1044
Official record on ClinicalTrials.gov — NCT04886895
Locations in the U.S.
| Ohio | Cincinnati Children's Hospital Medical Center, Cincinnati |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.