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Effect of Blenderized Enteral Tube Feeds on Pediatric Upper Gastrointestinal Tract Physiology

Who can join

Ages 1 and older · All sexes

Inclusion Criteria:

* Age 1-21 years
* G-tube
* Able to tolerate bolus gastric feeds over 30 minutes
* Use of conventional enteral formula
* Undergoing impedance study for clinical purposes

Exclusion Criteria:

* History of allergy or intolerance to any component of the test diets
* History of Nissen fundoplication (participants with suspected or documented unwrapped fundoplication will be eligible for participation)
* Current use of non-invasive pressure support (continuous or bi-level positive airway pressure)

About the study

Blenderized diets consist of a wide range of table foods such as fruits, vegetables, meat and legumes, pureed in a blender and administered via gastrostomy tube. In a recent study, the investigators reported that children receiving blenderized feeds via gastrostomy had fewer total admissions and respiratory admissions, total emergency room visits, and improved gastrointestinal symptom scores compared to those fed formula. The goal of this project is to understand how these diets affect gastroesophageal reflux burden.

What is being tested

• Elecare Jr (other)
• Nourish (other)
• Real Foods Blends (other)

Sponsor: Boston Children's Hospital · Participants: 45 · Started: Aug 1, 2021

Contact the study team

• Bridget M Hron, MD · Phone: 6173556058

Official record on ClinicalTrials.gov — NCT04900597

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.