Home › Non-Small Cell Lung Cancer › NCT04900935

Patient-centered, Optimal Integration of Survivorship and Palliative Care

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Age 18 or older
* MGH Cancer Center patient
* Within 6 months of diagnosis of metastatic NSCLC with oncogenic driver mutation (EGFR, ALK, ROS1, RET)
* Receiving targeted therapy
* Ability to respond in English or Spanish

Exclusion Criteria:

* Cognitive impairment or serious mental illness that limits ability to provide informed consent
* Need for urgent palliative care or hospice referral
* Pregnant women
* Prisoners

About the study

The goal of this study is to develop and test the feasibility of a supportive care model (POISE) for patients with metastatic Non-small Cell Lung Cancer (NSCLC). The main questions are

* is POISE feasible to deliver and acceptable to patients * what is the effect of POISE on the distress patients feel related to their uncertain future, their confidence in their ability to manage cancer, and their understanding about what to expect Participants in the randomized controlled trial will receive either the new supportive care model, POISE, which consists of four visits with a trained palliative care clinician, or care as usual, and will be asked to complete three surveys.

What is being tested

• POISE (behavioral)

Sponsor: Massachusetts General Hospital · Participants: 70 · Started: Sep 29, 2023

Contact the study team

• Laura A Petrillo, MD · Phone: (617) 724-4000

Official record on ClinicalTrials.gov — NCT04900935

Locations in the U.S.

Conditions

• Non-Small Cell Lung Cancer

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.