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Retinoblastoma Patient Clinical Database and Tissue Repository

RecruitingObservational study

Who can join

Ages 0 to 18 · All sexes

Full eligibility criteria
Inclusion Criteria:

* All patients, age 0 days to 18 years, with a diagnosis unilateral or bilateral retinoblastoma (RB) seen at CHLA (Children's Hospital Los Angeles).

Exclusion Criteria:

* Patients referred for second opinions only and not treated at CHLA for any reason.

About the study

Retinoblastoma (RB) is a primary eye cancer that forms in the back of the eye of infants and toddlers. Traditionally, RB is diagnosed without a biopsy; tumor can only be studied once an eye has been surgically removed.

Given this limitation, we use aqueous humor (AH), the clear fluid in the front of the eye to detect specific markers, or information, that comes from the tumor itself.

Sponsor: Children's Hospital Los Angeles · Participants: 800 · Started: Jan 1, 2017

Contact the study team

Official record on ClinicalTrials.gov — NCT04959097

Locations in the U.S.

ArizonaPhoenix Children's Hospital, Phoenix
CaliforniaChildren's Hospital Los Angeles, Los Angeles
GeorgiaEmory University Children's Healthcare of ATL, Atlanta
IllinoisAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago
OregonOregon Health & Science University: Casey Eye Institute, Portland
PennsylvaniaWills Eye Institute, Philadelphia
TennesseeSt. Jude Children's Research Hospital, Memphis
WashingtonSeattle Children's Hospital; University of Washington, Seattle

Conditions

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.