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Shear-wave Elastography Compared to Respiratory Function Testing

RecruitingHealthy volunteers welcome

Comparison of Shear-wave Elastography to State-of-the-art Respiratory Function Testing to Measure the Range of Forces Generated by the Diaphragm Muscle

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

\- Adult male and female healthy volunteers.

Exclusion Criteria:

* Volunteers who are pregnant.
* Volunteers with known pulmonary pathology (COPD, asthma requiring routine treatment).

About the study

The purpose of this study is to evaluate the relationship between transdiaphragmatic pressure (Pdi) and diaphragm shear-wave elastography (SWE) during state-of-the-art respiratory muscle testing including volitional efforts (e.g., maximal inspiratory pressure, maximal expiratory pressure, Valsalva maneuver), as well as maximal phrenic nerve stimulation.

What is being tested

Sponsor: Mayo Clinic · Participants: 24 · Started: Jul 28, 2021

Contact the study team

Official record on ClinicalTrials.gov — NCT04959526

Locations in the U.S.

MinnesotaMayo Clinic in Rochester, Rochester

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.