Home › Gender Dysphoria › NCT04979338
Development of Effective, Opioid Sparing Techniques for Peri-operative Pain Management of Transgender Patients Undergoing Gender Affirming Surgeries
RecruitingPhase 3
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Transgender persons 18 years and older * Undergoing gender affirming surgeries performed by either Dr. Maurice Garcia (orchiectomy only, vaginoplasty with or without canal \& orchiectomy, colon-vaginoplasty, \& peritoneal vaginoplasty; Stage I phalloplasty, or stage II phalloplasty); Dr. Edward Ray (feminizing chest surgery, masculinizing chest surgery, stage I phalloplasty); Dr. Amit Gupta (orchiectomy and peritoneal vaginoplasty only); or Dr. Yosef Nasseri (colon vaginoplasty surgery) Exclusion Criteria: * Patients who do not meet the inclusion criteria above * Any contraindications to the study drugs. * Patients with neurologic deficits that preclude them from sensing pain. * Patients with implanted pain neuromodulator devices (e.g., neurostimulator) * Patients who do not speak English
About the study
This study will compare the current standard-of-care pain treatment regimen options that are available to patients who undergo gender-affirming surgery. The purpose of this research is to determine if any of these options are more (versus less) effective than the others to manage surgery related pain, after surgery.
What is being tested
- Ultrasound guided Continuous Infraclavicular Brachial Plexus Block (other)
- Ultrasound guided Continuous Femoral Nerve Block (other)
- Ultrasound guided Pudendal Nerve Block (other)
- Bupivacaine (drug)
- Bilateral ultrasound guided Transversus Abdominis Plane Block (other)
- Bilateral spermatic cord block (other)
Sponsor: Cedars-Sinai Medical Center · Participants: 640 · Started: Nov 11, 2021
Contact the study team
- Jenna Stelmar, BS · Phone: 805-813-7882
Official record on ClinicalTrials.gov — NCT04979338
Locations in the U.S.
| California | Cedars-Sinai Medical Center - North and South Towers, Los Angeles |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.