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Study Comparing Local/ MAC Anesthesia in Lumbar Decompression

Randomized Study Comparing Local/ MAC Anesthesia to General for 1-3 Level Lumbar Decompressions

Who can join

Ages 40 to 95 · All sexes

Inclusion Criteria:

Patients with lumbar stenosis to be decompressed over 1-3 segments

* Ages 40-95
* Appropriate for general anesthesia

Exclusion Criteria:

* Planned significant nerve root retraction
* Previous fusion operation
* Unable to comply with follow up
* Patients with daily morphine equivalents or more 100mg
* Patients with a known hypersensitivity to propofol or any of DIPRIVAN Injectable Emulsion components.
* Patients with allergies to eggs, egg products, soybeans or soy products.

About the study

Explore efficacy, complications, and other factors associated with anaesthetic choice- To evaluate the efficacy of local + MAC as an alternative anesthetic to general anesthesia and to analyze patients' outcomes and experiences.

What is being tested

• Propofol Injection (drug)
• Lidocaine Hydrochloride, Injectable (drug)

Sponsor: Stanford University · Participants: 100 · Started: Dec 1, 2021

Contact the study team

• Sarah Miller, MAS · Phone: 650-725-7984

Official record on ClinicalTrials.gov — NCT04992572

Locations in the U.S.

Conditions

• Spinal Stenosis

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.