Home › Cerebral Palsy › NCT04997109
Telemedicine in Early Childhood Constraint Therapy in Cerebral Palsy
Recruiting
Who can join
4 Months – 13 Months · All sexes
Full eligibility criteria
Inclusion Criteria: * Aged 4 to 13 months, corrected age * Diagnosis of CP or classification of high-risk for CP as determined by published guidelines (\>95% risk of later CP) * Hammersmith Infant Neurological Exam (HINE) arm asymmetry score of greater than or equal to 2 and/or neuroimaging consistent with perinatal involvement * Hand Assessment for Infants (HAI) difference between hands ≥2, with an observable and relative difference in quality or amount of movement between hands, as determined by HAI-certified study therapists and/or a unimanual Bayley score difference between hands \>1 * Parent/legal guardian is able to provide informed consent Exclusion Criteria: * Congenital malformation of the brain or musculoskeletal system (MSK) * Receipt of botulinum toxin to the affected extremity within 3 months of study entry * Any prior long-term hard constraint programs
About the study
This study assesses two active treatments in different sequences and a standard of care group among infants with cerebral palsy.
What is being tested
- APPLES-tele (other)
- Parent-centered Approach (PCA) Support Intervention (behavioral)
- Standard of Care (behavioral)
Sponsor: Emory University · Participants: 267 · Started: Feb 23, 2022
Contact the study team
- Nathalie Maitre, MD, PhD · Phone: (678) 476-5332
Official record on ClinicalTrials.gov — NCT04997109
Locations in the U.S.
| Georgia | Emory University, Atlanta |
| Maryland | Kennedy Krieger Institute, Baltimore |
| Pennsylvania | Children's Hospital of Philadelphia, Philadelphia |
| Utah | The University of Utah, Salt Lake City |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.