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Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury
Recruiting
A Multisite Randomized Clinical Trial to Examine the Efficacy and Mechanisms of Immersive Virtual Walking Treatment for Neuropathic Pain in Spinal Cord Injury
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: The study will recruit individuals with complete injury (American Spinal Injury Association \[ASIA\] classification A) with lumbar, paraplegic, or low tetraplegic (C5-C7) injury. Additional criteria will include: 1. Must have persistent NP symptoms that are of daily severity of at least 4/10 for 3 or more months 2. Must endorse more than 2 items on a 7-item Spinal Cord Injury Pain Instrument, SCIPI 3. Must be 18 years of age or older 4. Must be more than one year post-injury to begin study (can be screened at an earlier time for eligibility) 5. Must have mobile connectivity with usable service 6. Must be stable on pain medication for 1 or more months 7. Must be cleared on the VRWalk physical activity clearance scale 8. Must not have motion sickness that interferes with daily life Exclusion Criteria: 1. Individuals with Injury levels between C1 and C4 2. Individuals under the age of 18 3. Individuals who were injured within the past year 4. Individuals who cannot comprehend spoken English 5. Individuals who are in prison 6. Individuals who are blind 7. Individuals who experience severe motion sickness
About the study
The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with chronic spinal cord injury.
What is being tested
- VR Game 1 (other)
- VR Game 2 (other)
Sponsor: Texas A&M University · Participants: 250 · Started: Nov 23, 2021
Contact the study team
- Amanda Sainz-Higgins, M.E.d · Phone: 804-569-5965
Official record on ClinicalTrials.gov — NCT05005026
Locations in the U.S.
| Alabama | University of Alabama at Birmingham, Birmingham |
| Texas | Texas A&M University, College Station |
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.