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Economic Incentives and vDOT for Latent Tuberculosis Infection
Economic Incentives and Video Directly Observed Therapy to Promote Adherence to Latent Tuberculosis Infection
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * 18 years old or older, * diagnosed with latent TB and determined to be appropriate for latent TB treatment by participants clinicians * reside in Baltimore metro area * speaks English or Spanish, or a language for which there is a short form available via the Johns Hopkins Medicine Institutional Review Board * prescribed 3 months Isoniazid/Rifapentine, prescribed 3 months Isoniazid/Rifampin, or 4 months Rifampin Exclusion Criteria: * younger than 18 years old * diagnosed with active TB * prescribed an alternative treatment regimen for latent TB * pregnant women (as determined by non-study directed clinical evaluation; BCHD performs urine pregnancy testing on women of child bearing age when indicated) * participant's spoken language does not have a translated long or short consent form
About the study
The purpose of this study is to evaluate a novel and scalable intervention that combines Video Directly Observed Therapy (vDOT) and financial incentives to promote completion of treatment for latent tuberculosis. Adult participants who are initiating treatment for latent tuberculosis will be recruited from the Baltimore City Health Department. The primary hypothesis is that the incentive intervention will increase the percentage of participants that complete the treatment for latent tuberculosis above the completion rates of participants receiving usual care.
What is being tested
- Usual Care (behavioral)
- Video Directly Observed Therapy alone (behavioral)
- Video Directly Observed Therapy plus Financial Incentives (behavioral)
Sponsor: Johns Hopkins University · Participants: 399 · Started: Feb 7, 2022
Contact the study team
- Principal Investigator · Phone: 443-287-0401
Official record on ClinicalTrials.gov — NCT05022862
Locations in the U.S.
| Maryland | Baltimore City Health Department, and Baltimore metropolitan area clinics and health departments, Baltimore |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.