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CONTOURA vs WFO Ablation PRK & LASIK

Topography-guided vs. Wavefront Optimized Corneal Refractive Surgery: A Prospective Contralateral Randomized Double-masked Study

Who can join

Ages 21 to 50 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Meet requirements for PRK or LASIK i.e., Stable \<= .5 D change MRSE)
* DOD beneficiaries age 21-50 years
* Local pts (w/i 60 mi) who will be in the area for at least 6 months post surgery
* Willing to complete all required follow-up visits

Exclusion Criteria:

* No meeting requirements for PRK or LASIK
* Desiring monovision treatment
* Anisometropia \>2D spherical equivalent
* Prior ocular surgeries / trauma / problem
* History of dry eyes
* Hyperopia
* Mixed astigmatism
* Inability to capture VARIO topolyzer scans
* Pregnant (or who plans to be within 6 months after surgery)
* Breastfeeding any time during the study
* History of herpetic disease

About the study

This is a prospective randomized contralateral double-masked study. Each patient will be randomized as to which eye undergoes wave-front optimized (WFO) vs. wave-front guided (WFG) during Photorefractive keratectomy (PRK) or Laser-assisted in situ Keratomileusis (LASIK) surgery to determine which ablation profile provides the best visual outcome.

What is being tested

• Wave-Front Optimized (WFO) ablation vs Topography-guided (TG) ablation (device)

Sponsor: 59th Medical Wing · Participants: 400 · Started: Apr 22, 2021

Contact the study team

• JOSE E CAPO-APONTE, OD, PhD · Phone: 210-292-2554
• AMBER MARTIN · Phone: 210-292-2483

Official record on ClinicalTrials.gov — NCT05037370

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.