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Liquid Biopsies in Pediatric Solid Tumors

RecruitingObservational studyHealthy volunteers welcome

Liquid Biopsies in Non-CNS Malignant Pediatric Solid Tumors

Who can join

6 Months · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Newly diagnosed, relapsed, or refractory histologically confirmed high grade bone or soft tissue sarcoma or malignant renal, thyroid, germ cell, or hepatic tumors, OR
* Healthy individual with no history of cancer or chronic medical problems and \< 21 years of age

Exclusion Criteria:

* CNS Malignancies
* Individuals \< 6 months of age

About the study

This study is being done to determine if traces of tumor can be found in the blood before, during, and after patients stop treatment. We will analyze the tumor material to see if it is similar to tumor tissue and if the tumor material in blood is helpful in monitoring the disease.

What is being tested

Sponsor: Children's Hospital Los Angeles · Participants: 320 · Started: May 8, 2019

Contact the study team

Official record on ClinicalTrials.gov — NCT05068583

Locations in the U.S.

CaliforniaChildren's Hospital Los Angeles, Los Angeles

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.