Home › Diabetic Eye Problems › NCT05079399
Biomarker of Diabetic Retinopathy
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Ability to cooperate with imaging procedures. * Health status: established type 2 diabetes * No history of panretinal photocoagulation (PRP) * No history of treatment with intravitreal agents for past 12 months Exclusion Criteria: * Previous or current malignancy * Acute or chronic infection (HIV, hepatitis B or C, tuberculosis) * Cerebral vascular accident or cerebral vascular procedure * Current pregnancy * History of organ transplantation * Presence of a graft (to avoid any effect of the graft) * History of previous vitrectomy * Subjects with a history of age-related macular degeneration age-related macular degeneration (AMD), glaucoma, uveitis, and branched or central vein occlusion.
About the study
Diabetic retinopathy (DR) is a complication of diabetes in which blood vessels supplying blood to the back of the eye (retina) are dysfunctional. This can lead to an improper supply of oxygen and nutrients to the retinal tissue, or it may trigger the formation of new blood vessels in response to the oxygen/nutrient deficiency. Ultimately affecting the normal vision. There is no known marker that will provide information on the health status of retinal blood vessels. Using highly specialized cells in the blood, this study will try to discover a marker of DR.
What is being tested
- Blood draw (other)
Sponsor: Indiana University · Participants: 192 · Started: Jan 1, 2022
Contact the study team
- Ashay D Bhatwadekar, PhD, RPh · Phone: 3172785075
- Amir R Hajrasouliha, MD · Phone: 3179441154
Official record on ClinicalTrials.gov — NCT05079399
Locations in the U.S.
| Indiana | Spring Mill Clinic, Carmel Eskenazi Eye Clinic, Indianapolis Glick Eye Institute, Indianapolis |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.