🔎 Trials Near Me

Home › Swallowing Disorders › NCT05108896

Aspiration in Acute Respiratory Failure Survivors 2

Recruiting

Aspiration in Acute Respiratory Failure Survivors

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

1. Admission to an ICU.
2. Mechanical ventilation with an endotracheal tube for greater than 48 hours.

Exclusion Criteria:

1. Likely persistent contraindications to enteral/oral nutrition administration.
2. Pre-existing history of dysphagia or aspiration.
3. Pre-existing or acute primary central or peripheral neuromuscular disorder.
4. Presence of a chronic tracheostomy (present prior to ICU admission).
5. Pre-existing head and neck cancer or surgery.
6. Coagulopathy resulting in uncontrolled nasal or pharyngeal bleeding.
7. Delirium for more than 96 hours after extubation as assessed by Confusion Assessment Method (CAM-ICU).
8. Extubated for greater than 96 hours.
9. Inability to obtain informed consent from patient or an appropriate surrogate.
10. Age \< 18 years.

About the study

The purpose of this study is to learn more about problems with swallowing that could develop in patients who are very sick and need a machine to help them breathe.

What is being tested

Sponsor: University of Colorado, Denver · Participants: 855 · Started: Dec 15, 2021

Contact the study team

Official record on ClinicalTrials.gov — NCT05108896

Locations in the U.S.

CaliforniaStanford Univerity, Stanford
ColoradoUniversity of Colorado, Aurora
ConnecticutYale University, New Haven
MassachusettsBoston University, Boston
Tufts Medical Center, Boston

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.