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Aspiration in Acute Respiratory Failure Survivors 2
Recruiting
Aspiration in Acute Respiratory Failure Survivors
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: 1. Admission to an ICU. 2. Mechanical ventilation with an endotracheal tube for greater than 48 hours. Exclusion Criteria: 1. Likely persistent contraindications to enteral/oral nutrition administration. 2. Pre-existing history of dysphagia or aspiration. 3. Pre-existing or acute primary central or peripheral neuromuscular disorder. 4. Presence of a chronic tracheostomy (present prior to ICU admission). 5. Pre-existing head and neck cancer or surgery. 6. Coagulopathy resulting in uncontrolled nasal or pharyngeal bleeding. 7. Delirium for more than 96 hours after extubation as assessed by Confusion Assessment Method (CAM-ICU). 8. Extubated for greater than 96 hours. 9. Inability to obtain informed consent from patient or an appropriate surrogate. 10. Age \< 18 years.
About the study
The purpose of this study is to learn more about problems with swallowing that could develop in patients who are very sick and need a machine to help them breathe.
What is being tested
- 3-Screenings Protocol (diagnostic test)
- FEES (diagnostic test)
- Tracheal Ultrasound (diagnostic test)
Sponsor: University of Colorado, Denver · Participants: 855 · Started: Dec 15, 2021
Contact the study team
- Jeff McKeehan, RN,MSN · Phone: 3037246080
Official record on ClinicalTrials.gov — NCT05108896
Locations in the U.S.
| California | Stanford Univerity, Stanford |
| Colorado | University of Colorado, Aurora |
| Connecticut | Yale University, New Haven |
| Massachusetts | Boston University, Boston Tufts Medical Center, Boston |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.