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Hot Flashes and Neurovascular Function in Women
RecruitingHealthy volunteers welcome
Who can join
Ages 40 to 60 · Women · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Non-smokers. * Non-obese. * Have at least one ovary. * Free from cardiovascular disease. * Not taking medications influencing cardiovascular function. Exclusion Criteria: \- None.
About the study
Women who experience hot flashes are at greater risk for hypertension and other cardiovascular disease. Neurovascular control mechanisms are likely to play an important role in this relationship. As such, these studies are designed to provide a major step forward in understanding the link between hot flashes and neurovascular dysfunction and, by extension, cardiovascular disease in women.
What is being tested
- Sympathoexcitatory stressors (other)
- Sodium Nitroprusside (drug)
- Acetylcholine (drug)
- Terbutaline (drug)
- Norepinephrine (drug)
Sponsor: Mayo Clinic · Participants: 120 · Started: Feb 24, 2022
Contact the study team
- Pamela A Engrav · Phone: 507-255-6938
- Nancy J Meyer · Phone: 507-255-0913
Official record on ClinicalTrials.gov — NCT05193968
Locations in the U.S.
| Minnesota | Mayo Clinic in Rochester, Rochester |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.