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tDCS With Cognitive Training to Reduce Impulsivity and Weight in Veterans With Obesity

Recruiting

Transcranial Direct Current Stimulation (tDCS) With Cognitive Training to Reduce Impulsivity and Weight in Veterans With Obesity: A Clinical Trial

Who can join

Ages 18 to 80 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Veteran enrolled in a MOVE! Weight Management Program (group or individual) at the Minneapolis VA Health Care System
* Obese (BMI\>30 or BMI\>27 plus at least one weight-related comorbidity)
* Able to understand English, self-consent and follow study-related procedures
* Willing to use a reliable form of birth control if they are of females of child-bearing potential

Exclusion Criteria:

* History of any of the following: seizures, severe or moderate head injury, head surgery, significant neurological disorder (significance based on Principal Investigator's judgment)
* Frequent severe headaches
* History of scalp conditions such as eczema or seborrheic dermatitis
* Metal in head (other than in mouth) including shrapnel/surgical clips/welding fragments
* Implanted medical devices (including pumps and cardiac pacemakers)
* Pregnancy
* Acute substance dependence or withdrawal that would affect ability to complete cognitive training
* Moderately severe to severe depression (as identified on PHQ-9 scale during baseline screening)
* Other psychological or medical disorders requiring inpatient treatment (as identified during chart review)
* Presence of a known metabolic or hormonal disorder (such as Cushing's, untreated thyroid dysfunction, or uncontrolled diabetes mellitus defined as a hemoglobin A1c \> 8.0), or significant edema/volume overload - all of which would affect weight
* Uncontrolled hypothyroidism that would affect weight

About the study

The purpose of this study is to investigate if transcranial direct current stimulation (tDCS) can increase the effectiveness of cognitive training to reduce impulsivity in individuals with obesity, and to evaluate weight change with these individuals. The long-term goal of this research is to develop new treatment approaches for individuals with obesity.

What is being tested

Sponsor: VA Office of Research and Development · Participants: 124 · Started: Nov 23, 2022

Contact the study team

Official record on ClinicalTrials.gov — NCT05225233

Locations in the U.S.

MinnesotaMinneapolis VA Health Care System, Minneapolis, MN, Minneapolis

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.