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Health and Resilience Projects: Foundations

Can Family-Centered Prevention Programming Reduce Neuroimmune Vulnerabilities for Drug Use and Cardiometabolic Risk Among African American Adolescents? A Randomized Prevention Trial

Who can join

Ages 10 to 13 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

Youth:

* Self reported African American or Black;
* Age 10-13

Parents:

* Primary caregiver for youth,
* Resides in same household as youth.

Exclusion Criteria:

Youth :

* Contraindications for MRI scanning (e.g., metal in body, traumatic brain injury, claustrophobia, pregnancy),
* Youth with chronic illnesses or medication regimens that would affect inflammatory panels (e.g., diabetes, congenital heart disease, asthma, cancers).

Parent:

* Conditions (e.g., severe disability, psychoses) that would prevent participation in the SAAF intervention or completing self-report measures.

About the study

The Health and Resilience Project (HARP): Foundations is investigating the efficacy of the Strong African American Families (SAAF) intervention in promoting the health and well being of African American adolescents. Youth age 10-13 and their primary caregivers are randomly assigned to receive SAAF or to a control group. Participants complete baseline and follow-up measures regarding vulnerability to substance use based on a neuroimmune model of stress coping.

What is being tested

• SAAF (behavioral)
• Receipt of parenting book (other)

Sponsor: University of Georgia · Participants: 650 · Started: Jan 25, 2022

Contact the study team

• Heather Zuercher, MPH · Phone: 706-425-2992
• Cara Hodge, BS · Phone: 706-425-2992

Official record on ClinicalTrials.gov — NCT05253235

Locations in the U.S.

Conditions

• Drug Use and Addiction

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.