Home › NCT05253352
Mapping and Quantifying Lymphatic Drainage of the Arm's Alternate Pathway
RecruitingObservational studyHealthy volunteers welcome
Variable Anatomy and Function of the Arm's Alternate Lymphatic Pathway
Who can join
Ages 18 and older · Women · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Female * History of breast cancer treatment including ALND - defined by removal of \>=10 lymph nodes - more than 2 years before study participation * Ability to understand the protocol and willingness to participate * At least 18 years of age Exclusion Criteria: * Prior history of bilateral lymph node surgery * Prior history of other surgical procedures of the affected upper extremity besides the axillary management for breast cancer treatment * Prior history of chronic inflammatory conditions (e.g. rheumatoid arthritis) * Prior history of filarial infections * Prior history of lymphedema * Patient-reported pregnancy * Patients who are breastfeeding * Iodine allergy * Prior history of upper extremity deep vein thrombosis * Prior history of congestive heart failure * Prior history of venous thoracic outlet syndrome * Current active cancer
About the study
Using indocyanine green (ICG) lymphography and lymphoscintigraphy with SPECT/CT imaging, the aim is to evaluate the anatomy of the lymphatic system pathway in two separate populations: healthy female volunteers and women with a history of breast cancer who did not develop lymphedema.
Sponsor: Beth Israel Deaconess Medical Center · Participants: 142 · Started: Apr 1, 2022
Contact the study team
- Angela Chen, BS · Phone: 6176327043
Official record on ClinicalTrials.gov — NCT05253352
Locations in the U.S.
| Massachusetts | Beth Israel Deaconess Medical Center, Boston |
From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.