Stimulation of the Larynx to Treat Unexplained Chronic Cough
Recruiting
Vibrotactile Stimulation of the Larynx to Treat Unexplained Chronic Cough
Who can join
Ages 18 to 88 · All sexes
Full eligibility criteria
Inclusion Criteria: * Adults aged 18-88 * \>8 weeks of cough * Cough visual analogue scale (VAS): Rating of 30 or greater on a 0-100 cough severity scale * Ability to provide informed consent and independently complete questionnaires * Ability to read and speak English Exclusion Criteria: * Electronic implants (e.g., pacemaker) * Currently doing speech therapy for cough * Contraindications to safe or effective VTS device use * No regular access to wifi internet Neuromuscular impairment that may affect cough/laryngeal sensation and/or function (e.g., multiple system atrophy, Parkinson, CVA, vocal fold paralysis or paresis) * Untreated carotid disease * BMI \> 40 (for transmission of VTS through soft tissue) * Current or recent (quit \< 3 months ago) smoking * Known currently infectious cause for cough (e.g., TB, pertussis, COVID) * History of known or suspected aspiration pneumonia * Diagnosis or clinical suspicion of chronic obstructive pulmonary disease (COPD) * Diagnosis or clinical suspicion of interstitial lung disease (ILD) * Unmanaged reflux * Unmanaged allergies/postnasal drip
About the study
Researchers will test the effect of non-invasive vibrotactile stimulation of the larynx on symptom severity of unexplained chronic cough.
What is being tested
- Vibrotactile Stimulation (device)
Sponsor: University of Minnesota · Participants: 60 · Started: Jul 13, 2021
Contact the study team
- Clinical Research Coordinators Ashley Ramaker, MS or colleagues · Phone: 612-625-3278
Official record on ClinicalTrials.gov — NCT05273190
Locations in the U.S.
| Minnesota | University of Minnesota, Minneapolis |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.