Use of Nasal Nitric Oxide Testing in Improving Primary Ciliary Dyskinesia Clinical Care

Inclusion Criteria:

* Individuals who are diagnosed with Primary Ciliary Dyskinesia OR
* Individuals with abnormal PCD diagnostics (abnormal ciliary biopsy or PCD genetics) OR
* Individuals with unexplained bronchiectasis OR
* Individuals undergoing PCD diagnostic testing (ciliary biopsy, PCD genetic testing) or concern based on clinical symptoms (at least two of the following):

  * Neonatal respiratory distress
  * Organ laterality defects
  * Year-round cough starting in first year of life or bronchiectasis on chest CT
  * Year-round nasal congestion starting in first year of life or pansinusitis
  * Multiple ear infections in the first two years of life with sequelae (e.g. ear tubes, chronic effusion, abnormal audiological exam)
  * History of recurrent pneumonias (at least 2 in one year or more than 3 at any time)
* Ability to provide consent for participation in study by the participants or guardian
* Ability to perform the test
* Age \>= 2 years of age

Exclusion Criteria:

* Individuals who are unable to understand the requirements of the study.
* Individuals (or guardians) who are unwilling to provide consent.
* Individuals who are unable to complete the testing
* Recent history of sinus surgery (within four weeks) or bloody nose (within one week) of testing (they can be included at a later date)
* Patients who are currently being treated (within one week) with antibiotics for sinusitis or respiratory symptoms (they can be included at a later date)
* Age \<2 years of age