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EyeConic: Qualification for Cone-Optogenetics

Qualification for Cone-Optogenetics (EyeConic)

Who can join

All ages · All sexes · Healthy volunteers welcome

Inclusion Criteria (patients):

* Diagnosis of generalized IRD
* Low vision as defined as visual acuity worse or equal to 0.05 (or 20/400) in the study eye
* Availability of macular optical coherence tomography (OCT)

Inclusion Criteria (controls):

* Normal ophthalmic findings
* Availability of macular optical coherence tomography (OCT)

Exclusion Criteria (all):

* Other eye diseases with a significant effect on vision or retinal structure
* Extraocular disease affecting retinal structure such as neurodegenerative diseases

About the study

This study aims to prepare for the first-in-human clinical trial of cone optogenetics vision restoration. As a first step, this worldwide multicenter ocular imaging study (EyeConic Study) is performed to identify eligible patients.

What is being tested

• Optical coherence tomography (OCT) (diagnostic test)

Sponsor: Institute of Molecular and Clinical Ophthalmology Basel · Participants: 1,000 · Started: Jul 1, 2021

Contact the study team

• Lucas Janeschitz-Kriegl, MD · Phone: +41787494373
• Tiana Koottungal · Phone: +41788486737

Official record on ClinicalTrials.gov — NCT05294978

Locations in the U.S.

Conditions

• Retinal Dystrophies
• Cone-Rod Dystrophies

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.